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Article

Genome-wide negative feedback drives transgenerational DNA methylation dynamics in Arabidopsis.

PLoS genetics - 1 Apr 2015

Ito Tasuku, Tarutani Yoshiaki, To Taiko Kim, Kassam Mohamed, Duvernois-Berthet Evelyne, Cortijo Sandra, Takashima Kazuya, Saze Hidetoshi, Toyoda Atsushi, Fujiyama Asao, Colot Vincent, Kakutani Tetsuji

Abstract excerpt

Epigenetic variations of phenotypes, especially those associated with DNA methylation, are often inherited over multiple generations in plants. The active and inactive chromatin states are heritable and can be maintained or even be amplified by positive feedback in a transgenerational manner. However, mechanisms controlling the transgenerational DNA methylation dynamics are largely unknown. As an approach to...

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PMID: 25902052
DOI: 10.1371/journal.pgen.1005154
PMCID: PMC4406451

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Source receipt: pubmed, retrieved 7 Sept 2026.

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