Article
Spatio-temporal expression of Prospero is finely tuned to allow the correct development and function of the nervous system in Drosophila melanogaster.
Developmental biology - 1 Apr 2007
Guenin Laure, Grosjean Yaël, Fraichard Stéphane, Acebes Angel, Baba-Aissa Fawzia, Ferveur Jean-François
Abstract excerpt
Adaptive animal behaviors depend upon the precise development of the nervous system that underlies them. In Drosophila melanogaster, the pan-neural prospero gene (pros), is involved in various aspects of neurogenesis including cell cycle control, axonal outgrowth, neuronal and glial cell differentiation. As these results have been generally obtained with null pros mutants inducing embryonic lethality, the role of...
Topics
- Animals
- DNA Primers
- Drosophila Proteins
- Drosophila melanogaster
- Gene Expression Regulation, Developmental
- In Situ Nick-End Labeling
- Nerve Tissue Proteins
- Nervous System
- Nuclear Proteins
- Phenotype
- Polymerase Chain Reaction
- Protein Isoforms
