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Article

Germline BCL-2 sequence variants and inherited predisposition to prostate cancer.

Prostate cancer and prostatic diseases - 1 Jan 2006

Kidd L R, Coulibaly A, Templeton T M, Chen W, Long L O, Mason T, Bonilla C, Akereyeni F, Freeman V, Isaacs W, Ahaghotu C, Kittles R A

Abstract excerpt

Apoptosis is an essential physiological process that regulates cellular proliferation. Here, we explored the effect of DNA sequence variation within the BCL-2 gene on prostate cancer susceptibility in three clinical populations, consisting of 428 African Americans, 214 Jamaicans and 218 European Americans. We observed a 70% reduced risk for prostate cancer among the European Americans who had possessed two copies...

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PMID: 16733517
DOI: 10.1038/sj.pcan.4500884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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