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Article

BCL2 Ala43Thr is a functional variant associated with protection against azoospermia in a Han-Chinese population.

Biology of reproduction - 1 Oct 2010

Ma Jun, Lu Hui-Yuan, Xia Yan-Kai, Dong Hui-Bin, Gu Ai-Hua, Li Zi-Yin, Li Zhong, Chen Ai-Min, Wang Xin-Ru, Wang Shou-Lin

Abstract excerpt

Apoptosis is very common during various stages of mammalian germ cell development and differentiation, and the BCL2 gene is one of the most important apoptotic regulators. Although its genetic variants are reported to be involved in cancers and autoimmune diseases, little information is available regarding BCL2 polymorphisms in male spermatogenesis. In the present study, single nucleotide polymorphisms (SNPs) in...

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Source

Identifiers

PMID: 20610805
DOI: 10.1095/biolreprod.109.082339

Genes

BCL2

Variants

rs1801018
rs1801018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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