Article
Haplotypes encoding the factor VIII 1241 Glu variation, factor VIII levels and the risk of venous thrombosis.
Thrombosis and haemostasis - 1 Jun 2006
Nossent A Yaël, Eikenboom Jeroen C J, Vos Hans L, Bakker Egbert, Tanis Bea C, Doggen Carine J M, Bertina Rogier M, Rosendaal Frits R
Abstract excerpt
Levels of factor VIII (FVIII) are associated with the risk of venous thrombosis. The FVIII variation D1241E has been reported to be associated with decreased levels of FVIII. Our objective was to study whether D1241E is associated with levels of FVIII and the risk of venous thrombosis and whether this association is caused by D1241E or another linked variation. We analyzed the association of three FVIII gene...
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