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Article

Factor XIII Val34Leu variant is protective against venous thromboembolism: a HuGE review and meta-analysis.

American journal of epidemiology - 15 Jul 2006

Wells Philip S, Anderson Josdalyne L, Scarvelis Dimitrios K, Doucette Steve P, Gagnon France

Abstract excerpt

It has been suggested that a G-to-T transition in exon 2 of the factor XIIIA gene resulting in a substitution of leucine for valine at amino acid 34 (FXIII Val34Leu) protects against venous thromboembolism (VTE). However, the evidence to date is insufficient to incorporate testing for the FXIII Val34Leu variant into clinical practice. To determine whether genotypes with the FXIII Val34Leu variant are protective...

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Identifiers

PMID: 16740590
DOI: 10.1093/aje/kwj179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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