Article
Factor VII and fibrinogen levels as risk factors for venous thrombosis. A case-control study of plasma levels and DNA polymorphisms--the Leiden Thrombophilia Study (LETS).
Thrombosis and haemostasis - 1 Jun 1994
Koster T, Rosendaal F R, Reitsma P H, van der Velden P A, Briët E, Vandenbroucke J P
Abstract excerpt
The plasma levels of coagulation factor VII and fibrinogen are well known risk factors for arterial thrombosis. We tested the hypothesis that this association also exists for venous thrombosis. Additionally, MspI and HaeIII polymorphisms in the factor VII and fibrinogen genes have recently been r...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Case-Control Studies
- Disease Susceptibility
- Factor VII
- Female
- Fibrinogen
- Gene Frequency
- Genotype
- Humans
- Male
- Middle Aged
- Netherlands
- Polymorphism, Restriction Fragment Length
- Risk Factors
- Thrombophlebitis