Article
Mouse myodystrophy (myd) mutation: refined mapping in an interval flanked by homology with distal human 4q.
Muscle & nerve. Supplement - 1 Jan 1995
Mathews K D, Mills K A, Bailey H L, Schelper R L, Murray J C
Abstract excerpt
Myodystrophy (myd) is an autosomal-recessive mouse mutation with dystrophic skeletal muscle. We propose that myd may be a model of the human disorder facioscapulohumeral dystrophy (FSHD) on the basis of clinical features and homologous genetic map locations. FSHD maps to human 4q35, while myd maps to mouse chromosome 8. To explore the relationship between FSHD and myd, it is necessary to define the homologous...
Topics
- Animals
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 4
- Disease Models, Animal
- Face
- Humans
- Humerus
- Mice
- Mice, Mutant Strains
- Molecular Probes