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Article

Novel transcripts of Nox1 are regulated by alternative promoters and expressed under phenotypic modulation of vascular smooth muscle cells.

The Biochemical journal - 1 Sept 2006

Arakawa Noriaki, Katsuyama Masato, Matsuno Kuniharu, Urao Norifumi, Tabuchi Yoshiaki, Okigaki Mitsuhiko, Matsubara Hiroaki, Yabe-Nishimura Chihiro

Abstract excerpt

NADPH oxidase is implicated in the pathogenesis of various cardiovascular disorders. In vascular smooth muscle cells (VSMC), expression of NOX1 (NADPH oxidase 1), a catalytic subunit of NADPH oxidase, is low and is induced upon stimulation by vasoactive factors, while it is abundantly expressed in colon epithelial cells. To clarify the regulatory mechanisms underlying such cell-specific expression, the upstream...

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Identifiers

PMID: 16724959
DOI: 10.1042/BJ20060300
PMCID: PMC1550311

Genes

NOX1

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Novel transcripts of Nox1 are regulated by alternative promoters and expressed under phenotypic modulation of vascular smooth muscle cells.PMID 16724959Read ↗

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