Article
Bcrp1 transcription in mouse testis is controlled by a promoter upstream of a novel first exon (E1U) regulated by steroidogenic factor-1.
Biochimica et biophysica acta - 1 Dec 2013
Xie Yi, Natarajan Karthika, Bauer Kenneth S, Nakanishi Takeo, Beck William T, Moreci Rebecca S, Jeyasuria Pancharatnam, Hussain Arif, Ross Douglas D
Abstract excerpt
Alternative promoter usage is typically associated with mRNAs with differing first exons that contain or consist entirely of a 5' untranslated region. The murine Bcrp1 (Abcg2) transporter has three alternative promoters associated with mRNAs containing alternative untranslated first exons designated as E1A, E1B, and E1C. The E1B promoter regulates Bcrp1 transcription in mouse intestine. Here, we report the...
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