Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Retrovirus infection strongly enhances scrapie infectivity release in cell culture.

The EMBO journal - 21 Jun 2006

Leblanc Pascal, Alais Sandrine, Porto-Carreiro Isabel, Lehmann Sylvain, Grassi Jacques, Raposo Graça, Darlix Jean Luc

Abstract excerpt

Prion diseases are neurodegenerative disorders associated in most cases with the accumulation in the central nervous system of PrPSc (conformationally altered isoform of cellular prion protein (PrPC); Sc for scrapie), a partially protease-resistant isoform of the PrPC. PrPSc is thought to be the causative agent of transmissible spongiform encephalopathies. The mechanisms involved in the intercellular transfer of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Products, gag
Share to Moloney murine leukemia virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to NIH 3T3 Cells

Share to PrPC Proteins

Share to PrPSc Proteins

Share to Retroviridae Infections

Share to Scrapie

Share to Virion

Source

Open in PubMed Open full text

Identifiers

PMID: 16724107
DOI: 10.1038/sj.emboj.7601162
PMCID: PMC1500854

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Retrovirus infection strongly enhances scrapie infectivity release in cell culture.PMID 16724107Read ↗

Mouse neuroblastoma cells release prion infectivity associated with exosomal vesiclesSemantic proximity Read ↗

Functional mechanisms of the cellular prion protein (PrP(C)) associated anti-HIV-1 properties.Semantic proximity Read ↗

Persistent retroviral infection with MoMuLV influences neuropathological signature and phenotype of prion disease.Semantic proximity Read ↗

Analysis of the interactions between HIV-1 and the cellular prion protein in a human cell line.Semantic proximity Read ↗

Endogenous retroviruses promote prion-like spreading of proteopathic seedsSemantic proximity Read ↗

Prion protein PrP nucleic acid binding and mobilization implicates retroelements as the replicative component of transmissible spongiform encephalopathySemantic proximity Read ↗

Small-ruminant lentivirus enhances PrPSc accumulation in cultured sheep microglial cells.Semantic proximity Read ↗

Stimulation of PrP(C) retrograde transport toward the endoplasmic reticulum increases accumulation of PrP(Sc) in prion-infected cells.Semantic proximity Read ↗

Inhibition of PrPSc formation by lentiviral gene transfer of PrP containing dominant negative mutations.Semantic proximity Read ↗

Identification of intermediate steps in the conversion of a mutant prion protein to a scrapie-like form in cultured cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.