Article
The dsRNA binding site of human Toll-like receptor 3.
Proceedings of the National Academy of Sciences of the United States of America - 6 Jun 2006
Bell Jessica K, Askins Janine, Hall Pamela R, Davies David R, Segal David M
Abstract excerpt
Pathogen recognition by Toll-like receptors (TLRs) initiates innate immune responses that are essential for inhibiting pathogen dissemination and for the development of acquired immunity. The TLRs recognize pathogens with their N-terminal ectodomains (ECD), but the molecular basis for this recogn...
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