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Article

The toll-like receptor 3:dsRNA signaling complex.

Biochimica et biophysica acta - 1 Jan 2000

Botos Istvan, Liu Lin, Wang Yan, Segal David M, Davies David R

Abstract excerpt

Toll-like receptors (TLRs) recognize conserved molecular patterns in invading pathogens and trigger innate immune responses. TLR3 recognizes dsRNA, a molecular signature of most viruses via its ectodomain (ECD). The TLR3-ECD structure consists of a 23 turn coil bent into the shape of a horseshoe...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19595807
DOI: 10.1016/j.bbagrm.2009.06.005
PMCID: PMC2784288

Genes

TLR3
ECD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19595807-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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