Article
Characterization of the recombinant MutY homolog, an adenine DNA glycosylase, from yeast Schizosaccharomyces pombe.
The Journal of biological chemistry - 25 Sept 1998
Lu A L, Fawcett W P
Abstract excerpt
The mutY homolog (SpMYH) gene from a cDNA library of Schizosaccharomyces pombe encodes a protein of 461 amino acids that displays 28 and 31% identity to Escherichia coli MutY and human MutY homolog (MYH), respectively. Expressed SpMYH is able to complement an E. coli mutY mutant to reduce the mut...
Topics
- Amino Acid Sequence
- Base Sequence
- DNA Glycosylases
- DNA Primers
- Edetic Acid
- Escherichia coli
- Kinetics
- Molecular Sequence Data
- Mutation
- N-Glycosyl Hydrolases
- Nucleic Acid Heteroduplexes
- Protein Binding
- Recombinant Proteins
- Salts
- Schizosaccharomyces
- Sequence Homology, Amino Acid
- Substrate Specificity