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Genetic polymorphism of CYP2C19 in a Jordanian population: influence of allele frequencies of CYP2C191 and CYP2C192 on the pharmacokinetic profile of lansoprazole.

Molecular biology reports - 1 Apr 2012

Zalloum Imad, Hakooz Nancy, Arafat Tawfiq

Abstract excerpt

To relate the pharmacokinetics of orally administered lansoprazole in healthy adult Jordanian men with CYP2C19 polymorphisms and to determine the percentage of CYP2C19 polymorphism in Jordanian population and the allelic frequency of CYP2C19*2 and CYP2C19*3. A total of 78 healthy Jordanian volunteers were included in this study from three different bioequivalence studies, one of these studies which included 26...

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PMID: 21769476
DOI: 10.1007/s11033-011-1204-5

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