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Article

Glutathione S-transferase polymorphisms and ochratoxin A toxicity in primary human urothelial cells.

Toxicology - 5 Jul 2006

Lebrun Stefan, Golka Klaus, Schulze Harald, Föllmann Wolfram

Abstract excerpt

The mycotoxin ochratoxin A (OTA) is a worldwide contaminant of human food. OTA is genotoxic, immunotoxic, teratogenic and carcinogenic in rodents and can cause nephropathy in pigs. High amounts of OTA can cause nephropathy in humans. Moreover, evidence has been accumulated that OTA is a genotoxic carcinogen. Nevertheless, the mechanism that leads to OTA toxicity has not been fully resolved and it is discussed if...

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Source

Identifiers

PMID: 16716482
DOI: 10.1016/j.tox.2006.04.034

Genes

GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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