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Article

Gene polymorphisms against DNA damage induced by hydrogen peroxide in leukocytes of healthy humans through comet assay: a quasi-experimental study.

Environmental health : a global access science source - 5 May 2010

Miranda-Vilela Ana L, Alves Penha Cz, Akimoto Arthur K, Lordelo Graciana S, Gonçalves Carlos A, Grisolia Cesar K, Klautau-Guimarães Maria N

Abstract excerpt

BACKGROUND: Normal cellular metabolism is well established as the source of endogenous reactive oxygen species which account for the background levels of oxidative DNA damage detected in normal tissue. Hydrogen peroxide imposes an oxidative stress condition on cells that can result in DNA damage, leading to mutagenesis and cell death. Several potentially significant genetic variants related to oxidative stress...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20444272
DOI: 10.1186/1476-069X-9-21
PMCID: PMC2881052

Genes

ACE
CAT
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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