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Article

The APOA1/C3/A4/A5 gene cluster, lipid metabolism and cardiovascular disease risk.

Current opinion in lipidology - 1 Apr 2005

Lai Chao-Qiang, Parnell Laurence D, Ordovas Jose M

Abstract excerpt

PURPOSE OF REVIEW: APOA1/C3/A4/A5 are key components modulating lipoprotein metabolism and cardiovascular disease risk. This review examines the evidence regarding linkage disequilibrium and haplotype structure within the A1/C3/A4/A5 cluster, and assesses its association with plasma lipids and cardiovascular disease risk. In addition, we use genomic information from several species to draw inferences about the...

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Source

Identifiers

PMID: 15767855
DOI: 10.1097/01.mol.0000162320.54795.68

Genes

APOA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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