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Article

Phosphorylation of JAK2 at serine 523: a negative regulator of JAK2 that is stimulated by growth hormone and epidermal growth factor.

Molecular and cellular biology - 1 Jun 2006

Mazurkiewicz-Munoz Anna M, Argetsinger Lawrence S, Kouadio Jean-Louis K, Stensballe Allan, Jensen Ole N, Cline Joel M, Carter-Su Christin

Abstract excerpt

The tyrosine kinase JAK2 is a key signaling protein for at least 20 receptors in the cytokine/hematopoietin receptor superfamily and is a component of signaling for multiple receptor tyrosine kinases and several G-protein-coupled receptors. In this study, phosphopeptide affinity enrichment and mass spectrometry identified serine 523 (Ser523) in JAK2 as a site of phosphorylation. A phosphoserine 523 antibody...

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Identifiers

PMID: 16705159
DOI: 10.1128/MCB.01591-05
PMCID: PMC1489095

Genes

JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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