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Article

Role of tyrosine kinase Jak2 in prolactin-induced differentiation and growth of mammary epithelial cells.

The Journal of biological chemistry - 19 Apr 2002

Xie Jianwu, LeBaron Matthew J, Nevalainen Marja T, Rui Hallgeir

Abstract excerpt

Genetic studies in mice have established a critical role for prolactin receptors and transcription factor Stat5 in mammary gland differentiation. However, the enzymatic coupling between prolactin receptors and Stat5 in this process has not been established. In addition to Jak2, several other tyrosine kinases reportedly also are associated with prolactin receptors and may phosphorylate Stat5. Because Jak2 null...

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Source

Identifiers

PMID: 11821424
DOI: 10.1074/jbc.M112399200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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