Article
Plasminogen activator inhibitor-1 promoter polymorphism is not associated with the aggressiveness of disease in prostate cancer.
Clinical oncology (Royal College of Radiologists (Great Britain)) - 1 May 2006
Li H, Shinohara E T, Cai Q, Chen H, Courtney R, Cao C, Wang Z, Teng M, Zheng W, Lu B
Abstract excerpt
AIMS: PAI-1 (plasminogen activator inhibitors-1) regulates plasminogen activation, and is related to tumour development. This study aims to test whether the promoter polymorphism in the PAI-1 gene is related to the aggressiveness of disease in prostate cancer. MATERIALS AND METHODS: In the present study, Taqman SNP genotyping assay was used to detect PAI-1 4G/5G polymorphism in DNA from paraffin-embedded tissues...
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