Article
Role of MMP-1 1G/2G promoter gene polymorphism on the development of prostate cancer in the Turkish population.
Urologia internationalis - 1 Jan 2007
Albayrak Selami, Cangüven Onder, Göktaş Cemal, Aydemir Hüseyin, Köksal Vedat
Abstract excerpt
INTRODUCTION: To investigate the association of 1G/2G polymorphism in matrix metalloproteinase-1 (MMP-1) promoter with susceptibility to prostate carcinoma in the Turkish population. MATERIALS AND METHODS: MMP-1 promoter polymorphism was genotyped by PCR-RFLP analysis in 55 prostate cancer patients and 43 healthy controls. RESULTS: The frequency of 1G/2G genotypes in prostate cancer patients was similar to that...
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