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Article

Polymorphisms in the prostate-specific antigen gene promoter do not predict serum prostate-specific antigen levels in African-American men.

Prostate cancer and prostatic diseases - 1 Jan 2006

Beebe-Dimmer J L, Lange L A, Cain J E, Lewis R C, Ray A M, Sarma A V, Lange E M, Cooney K A

Abstract excerpt

A major problem with the use of serum prostate-specific antigen (PSA) in predicting prostate cancer risk is the considerable variability of such measurements. Cramer et al. identified a set of single-nucleotide polymorphisms (SNPs) in the upstream regulatory region of the PSA gene that were each associated with increased promoter activity and serum PSA, further suggesting that genotyping these SNPs could be...

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Identifiers

PMID: 16247489
DOI: 10.1038/sj.pcan.4500840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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