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Article

Enhanced metastatic dissemination to multiple organs by melanoma and lymphoma cells in timp-3-/- mice.

Oncogene - 19 Oct 2006

Cruz-Munoz W, Sanchez O H, Di Grappa M, English J L, Hill R P, Khokha R

Abstract excerpt

Identifying versatile inhibitors of metastasis that operate in multiple sites against distinct cancer cell types is important for designing novel therapeutics for metastasis. We show that multiple tissues of timp-3-/- mice are more susceptible to metastatic colonization. Overall, a 5-14-fold increase in liver and kidney colonization occurred by EL-4 lymphoma cells, and a twofold increase upon targeting B16F10...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16702949
DOI: 10.1038/sj.onc.1209663

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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