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Article

Analysis of IL-10, IL-4 and TNF-alpha polymorphisms in drug-induced liver injury (DILI) and its outcome.

Journal of hepatology - 1 Jul 2008

Pachkoria Ketevan, Lucena M Isabel, Crespo Esperanza, Ruiz-Cabello Francisco, Lopez-Ortega Susana, Fernandez M A Carmen, Romero-Gomez Manuel, Madrazo Ana, Durán Jose Antonio, de Dios Ana Malcon, Borraz Yolanda, Navarro Jose Maria, Andrade Raúl J

Abstract excerpt

BACKGROUND/AIMS: The aim of this study was to assess whether genetic polymorphism of three important candidate cytokine genes, IL-10 (-1082G/A, -819C/T, and -592C/A), IL-4 (-590C/T) and TNF-alpha (-308G/A), play a role in the susceptibility to developing drug-induced liver injury (DILI), and in determining its phenotypic expression and severity. METHODS: Cytokine genotyping was analysed using TaqMan 5' allelic...

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PMID: 18485518
DOI: 10.1016/j.jhep.2008.03.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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