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Article

Interleukin 10 promoter region polymorphisms and susceptibility to advanced alcoholic liver disease.

Gut - 1 Apr 2000

Grove J, Daly A K, Bassendine M F, Gilvarry E, Day C P

Abstract excerpt

BACKGROUND: The factors determining why less than 10% of heavy drinkers develop advanced alcoholic liver disease (ALD) remain elusive, although genetic factors may be important. Interleukin 10 (IL-10) is an important cytokine with anti-inflammatory, anti-immune, and antifibrotic functions. Several polymorphisms have been identified in the IL-10 promoter and recent evidence suggests that some of these may have...

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Source

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Identifiers

PMID: 10716685
DOI: 10.1136/gut.46.4.540
PMCID: PMC1727883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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