Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytokine gene polymorphisms in acute pancreatitis.

JOP : Journal of the pancreas - 1 Jul 2000

Sargen K, Demaine A G, Kingsnorth A N

Abstract excerpt

CONTEXT: Pro-inflammatory and regulatory cytokines play a key role in the pathogenesis of acute pancreatitis. Genetic loci encoding cytokines have been shown to be polymorphic, in some cases influencing protein expression. OBJECTIVE: To investigate if TNF and IL-10 gene loci are associated with the occurrence or severity of acute pancreatitis. SETTING: Acute surgical unit within large district hospital serving a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to Cytokines
Share to Genetic Markers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-10

Share to Microsatellite Repeats

Share to Pancreatitis

Share to Severity of Illness Index

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 11852287

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytokine gene polymorphisms in acute pancreatitis.PMID 11852287Read ↗

Cytokine genotypes in acute pancreatitis: association with etiology, severity, and cytokine levels in blood.Semantic proximity Read ↗

Evidence against a role for polymorphisms at tumor necrosis factor, interleukin-1 and interleukin-1 receptor antagonist gene loci in the regulation of disease severity in acute pancreatitis.Semantic proximity Read ↗

Influence of cytokine and ICAM-1 gene polymorphisms on susceptibility to chronic pancreatitis.Semantic proximity Read ↗

Polymorphism of cytokine genes (TGF-beta1, IFN-gamma, IL-6, IL-10, and TNF-alpha) in patients with chronic pancreatitis.Semantic proximity Read ↗

The -251 A/T Polymorphism in the IL8 Promoter is a Risk Factor for Acute Pancreatitis.Semantic proximity Read ↗

A single-nucleotide polymorphism in tumor necrosis factor-α (-308 G/A) as a biomarker in chronic pancreatitis.Semantic proximity Read ↗

Polymorphisms in tumour necrosis factor alpha (TNFalpha) gene in patients with acute pancreatitis.Semantic proximity Read ↗

TNF-alpha gene (TNFA) variants increase risk for multi-organ dysfunction syndrome (MODS) in acute pancreatitis.Semantic proximity Read ↗

Lack of association between TNF-α gene promoter polymorphisms and pancreatitis: a meta-analysis.Semantic proximity Read ↗

The role of cytokine gene polymorphisms in determining disease susceptibility and phenotype in inflammatory bowel disease.Semantic proximity Read ↗

Analysis of tumor necrosis factor-alpha, transforming growth factor-beta 1, interleukin-10, and interferon-gamma polymorphisms in patients with alcoholic chronic pancreatitis.Semantic proximity Read ↗

Influence of interleukin gene polymorphisms on development of acute pancreatitis: a systematic review and meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.