Article
Low-dose alcohol actions on alpha4beta3delta GABAA receptors are reversed by the behavioral alcohol antagonist Ro15-4513.
Proceedings of the National Academy of Sciences of the United States of America - 30 May 2006
Wallner M, Hanchar H J, Olsen R W
Abstract excerpt
Although it is now more than two decades since it was first reported that the imidazobenzodiazepine Ro15-4513 reverses behavioral alcohol effects, the molecular target(s) of Ro15-4513 and the mechanism of alcohol antagonism remain elusive. Here, we show that Ro15-4513 blocks the alcohol enhanceme...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
