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Disease relevant HLA class II alleles isolated by genotypic, haplotypic, and sequence analysis in North American Caucasians with pemphigus vulgaris.

Human immunology - 1 Jan 2000

Lee Erica, Lendas Katherine A, Chow Selwyn, Pirani Yasmin, Gordon Derek, Dionisio Robert, Nguyen Daniela, Spizuoco Amy, Fotino Marilena, Zhang Yun, Sinha Animesh A

Abstract excerpt

Early studies of genetic susceptibility to pemphigus vulgaris (PV) showed associations between human leukocyte antigen (HLA) DR4 and DR6 and disease. The emergence of DNA sequencing techniques has implicated numerous DRB1 and DQB1 loci in various populations, leading to confusion regarding which exact alleles confer susceptibility. The strong linkage disequilibrium among DR and DQ HLA alleles further complicates...

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PMID: 16698434
DOI: 10.1016/j.humimm.2005.09.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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