Article
HLA-G is associated with pemphigus vulgaris in Jewish patients.
Human immunology - 1 Jan 2004
Gazit Ephraim, Slomov Yelena, Goldberg Ilan, Brenner Sarah, Loewenthal Ron
Abstract excerpt
Pemphigus is a group of life-threatening autoimmune blistering diseases of the skin and mucous membranes. The etiology and pathogenesis of this destructive autoimmune process remains unknown, but significant association with human leukocyte antigen (HLA) factors have been described in pemphigus vulgaris (PV) patient cohorts worldwide. We have recently analyzed DNA samples obtained from pemphigus patients and...
Topics
- Alleles
- Case-Control Studies
- Exons
- Gene Frequency
- Genetic Markers
- Genetic Predisposition to Disease
- HLA Antigens
- HLA-A Antigens
- HLA-B Antigens
- HLA-DR Antigens
- HLA-DRB1 Chains
- HLA-G Antigens
- Histocompatibility Antigens Class I
- Humans
- Jews
- Microsatellite Repeats
- Mutagenesis, Insertional
- Pemphigus
