Article
Human leukocyte antigen class II (DRB1 and DQB1) alleles and haplotypes frequencies in patients with pemphigus vulgaris among the Serbian population.
HLA - 1 May 2016
Zivanovic D, Bojic S, Medenica L, Andric Z, Popadic D
Abstract excerpt
The etiology of pemphigus vulgaris (PV) is multifactorial and includes genetic, environmental, hormonal, and immunological factors. Inheritance of certain Human class II leukocyte antigen (HLA) alleles is by far the best-established predisposing factor for the development of PV. Class II HLA alleles vary among racial/ethnic backgrounds. We have determined an association between HLA class II alleles and PV among...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Case-Control Studies
- Female
- Gene Frequency
- HLA-DQ beta-Chains
- HLA-DRB1 Chains
- Haplotypes
- Humans
- Male