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Article

Identification of two gene variants associated with risk of advanced fibrosis in patients with chronic hepatitis C.

Gastroenterology - 1 May 2006

Huang Hongjin, Shiffman Mitchell L, Cheung Ramsey C, Layden Thomas J, Friedman Scott, Abar Olivia T, Yee Linda, Chokkalingam Anand P, Schrodi Steven J, Chan Jason, Catanese Joseph J, Leong Diane U, Ross David, Hu Xiaolan, Monto Alexander, McAllister Linda B, Broder Samuel, White Thomas, Sninsky John J, Wright Teresa L

Abstract excerpt

BACKGROUND & AIMS: Previously identified clinical risk factors such as sex, alcohol consumption, and age at infection do not accurately predict which patients with chronic hepatitis C (CHC) will develop advanced fibrosis (bridging fibrosis and cirrhosis). The aim of this study was to identify genetic polymorphisms that can predict the risk of advanced fibrosis in patients with CHC. METHODS: A total of 916...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16697732
DOI: 10.1053/j.gastro.2006.02.032

Genes

DDX5
POLG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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