Article
PARK2 polymorphisms predict disease progression in patients infected with hepatitis C virus.
Annals of hepatology - 1 Jan 2000
Al-Qahtani Ahmed A, Al-Anazi Mashael R, Al-Zoghaibi Fahad A, Abdo Ayman A, Sanai Faisal M, Al-Hamoudi Waleed K, Alswat Khalid A, Al-Ashgar Hamad I, Khan Mohammed Q, Albenmousa Ali, Khalak Hanif, Al-Ahdal Mohammed N
Abstract excerpt
Background. The protein encoded by PARK2 gene is a component of the ubiquitin-proteasome system that mediates targeting of proteins for the degradation pathway. Genetic variations at PARK2 gene were linked to various diseases including leprosy, typhoid and cancer. The present study investigated the association of single nucleotide polymorphisms (SNPs) in the PARK2 gene with the development of hepatitis C virus...
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