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Article

Differential promoter usage for insulin-like growth factor-II gene in Chinese hepatocellular carcinoma with hepatitis B virus infection.

Cancer detection and prevention - 1 Jan 2006

Tang Shao Hui, Yang Dong Hua, Huang Wei, Zhou Min, Zhou Hong Ke, Lu Xiao Hua, Ye Gang

Abstract excerpt

BACKGROUND: Human insulin-like growth factor-II (IGF-II) gene contains nine exons and four different promoters (P1-P4). Expression of the gene is elevated in the preneoplastic hepatic foci and hepatocellular carcinoma (HCC) of experimental animals and humans. To gain insight into transcriptional regulation of the gene in HCC, we analyzed the relative usage of the P1-P4 promoters and its correlation with the...

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Share to Carcinoma, Hepatocellular
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Identifiers

PMID: 16697535
DOI: 10.1016/j.cdp.2005.12.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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