Article
The EGF A61G polymorphism is associated with disease-free period and survival in malignant melanoma.
The Journal of investigative dermatology - 1 Oct 2006
Okamoto Ichiro, Roka Florian, Krögler Julia, Endler Georg, Kaufmann Stefan, Tockner Silvia, Marsik Claudia, Jilma Bernd, Mannhalter Christine, Wagner Oswald, Pehamberger Hubert
Abstract excerpt
An earlier study reported that a common polymorphism in the 5' untranslated region of the epidermal growth factor (EGF) gene is associated with increased risk for cutaneous malignant melanoma (MM) and Breslow thickness. Since then, several independent studies have reported conflicting results that have challenged this hypothesis. However, none of the previous studies examined survival as the primary outcome. We...
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