Article
Arteriogenesis depends on circulating monocytes and macrophage accumulation and is severely depressed in op/op mice.
Journal of leukocyte biology - 1 Jul 2006
Bergmann Caroline E, Hoefer Imo E, Meder Benjamin, Roth Holger, van Royen Niels, Breit Sabine M, Jost Marco M, Aharinejad Seyedhossein, Hartmann Susanne, Buschmann Ivo R
Abstract excerpt
It has been suggested that monocytes/macrophages represent the pivotal cell type during early adaptive growth of pre-existent arterial anastomoses toward functional collateral arteries (arteriogenesis) upon arterial occlusion. This hypothesis was supported by previous studies providing evidence that elevation of the peripheral monocyte count, increased monocyte survival (e.g., granulocyte macrophage-colony...
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