Article
Selective subepicardial localization of monocyte subsets in response to progressive coronary artery constriction.
American journal of physiology. Heart and circulatory physiology - 1 Jul 2016
Hakimzadeh Nazanin, van Lier Monique G J T B, van Horssen Pepijn, Daal Mariah, Ly Duy Ha, Belterman Charly, Coronel Ruben, Spaan Jos A E, Siebes Maria
Abstract excerpt
Following myocardial infarction and atherosclerotic lesion development, monocytes contribute to myocardial protection and repair, while also partaking in myocardial ischemic injury. The balance of proinflammatory and reparative monocyte subsets is crucial in governing these therapeutic and pathological outcomes. Myocardial ischemic damage displays heterogeneity across the myocardium, whereby the subendocardium...
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