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Article

Reduced macrophage-dependent inflammation improves endothelin-1-induced vascular injury.

Hypertension (Dallas, Tex. : 1979) - 1 Jul 2013

Javeshghani Danesh, Barhoumi Tlili, Idris-Khodja Nourredine, Paradis Pierre, Schiffrin Ernesto L

Abstract excerpt

Transgenic mice with endothelium-specific endothelin-1 (ET-1) overexpression exhibit endothelial dysfunction and vascular remodeling, oxidative stress, and inflammation. We previously observed that monocytes/macrophages play a role in angiotensin II, aldosterone, and deoxycorticosterone acetate/salt-induced vascular remodeling, oxidative stress, and inflammation using a model with reduced monocytes/macrophages,...

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Share to Endothelin-1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23670300
DOI: 10.1161/HYPERTENSIONAHA.113.01298

Genes

CSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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