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Article

Molecular mechanism of inhibitory aryl hydrocarbon receptor-estrogen receptor/Sp1 cross talk in breast cancer cells.

Molecular endocrinology (Baltimore, Md.) - 1 Sept 2006

Khan Shaheen, Barhoumi Rola, Burghardt Robert, Liu Shengxi, Kim Kyounghyun, Safe Stephen

Abstract excerpt

The trifunctional carbamoylphosphate synthetase/aspartate transcarbamyltransferase/dihydroorotase (CAD) gene is hormone responsive in MCF-7 and ZR-75 breast cancer cells, and this response is inhibited by the aryl hydrocarbon receptor (AhR) agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Estr...

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Share to Aspartate Carbamoyltransferase
Share to Cytochrome P-450 CYP1A1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Estrogen Receptor alpha

Share to Fluorescence Resonance Energy Transfer

Share to Polychlorinated Dibenzodioxins

Share to Receptors, Aryl Hydrocarbon

Share to Sp1 Transcription Factor

Source

Identifiers

PMID: 16675542
DOI: 10.1210/me.2006-0100

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16675542-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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