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Article

Analysis of the transcriptional regulation and molecular function of the aryl hydrocarbon receptor repressor in human cell lines.

Drug metabolism and disposition: the biological fate of chemicals - 1 Dec 2007

Haarmann-Stemmann Thomas, Bothe Hanno, Kohli Amitabh, Sydlik Ulrich, Abel Josef, Fritsche Ellen

Abstract excerpt

The aryl hydrocarbon receptor repressor (AhRR) is a member of the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. The AhRR was described as a feedback modulator, which counteracts AhR-dependent gene expression. We investigated the molecular mechanisms of transcriptional regulation of the human AhRR by cloning its...

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Identifiers

PMID: 17890447
DOI: 10.1124/dmd.107.016253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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