Article
A tetratricopeptide repeat half-site in the aryl hydrocarbon receptor is important for DNA binding and trans-activation potential.
Molecular pharmacology - 1 Dec 2000
Levine S L, Petrulis J R, Dubil A, Perdew G H
Abstract excerpt
Similar to certain unliganded steroid hormone receptor complexes, the unliganded aryl hydrocarbon receptor has been shown to consist of a multimeric core complex that includes the 90-kDa heat shock protein (hsp90) and the immunophilin-like hepatitis B X-associated protein 2 (XAP2). Immunophilins and XAP2 associated with these complexes bind to the carboxyl-terminal end of hsp90 through an interaction with their...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
