Article
A novel zinc-carboxypeptidase SURO-1 regulates cuticle formation and body morphogenesis in Caenorhabditis elegans.
FEBS letters - 3 Jan 2011
Kim Tai Hoon, Kim Yeon Jung, Cho Jin Won, Shim Jaegal
Abstract excerpt
Cuticle formation and molting are critical for the development of Caenorhabditis elegans. To understand cuticle formation more clearly, we screened for suppressors in transgenic worms that expressed dominant ROL-6 collagen proteins. The suro-1 mutant, which is mild dumpy, exhibited a different ROL-6::GFP localization pattern compared to other Dpy mutants. We identified mutations in three suro-1 mutants, and found...
Topics
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Carboxypeptidases
- Collagen
- Epidermis
- Female
- Green Fluorescent Proteins
- HeLa Cells
- Humans
- Male
