Article
dpy-18 encodes an alpha-subunit of prolyl-4-hydroxylase in caenorhabditis elegans.
Genetics - 1 Jul 2000
Hill K L, Harfe B D, Dobbins C A, L'Hernault S W
Abstract excerpt
Collagen is an extracellular matrix (ECM) component encoded by a large multigene family in multicellular animals. Procollagen is post-translationally modified by prolyl-4-hydroxylase (EC 1.14.11.2) before secretion and participation in ECM formation. Therefore, collagen processing and regulation can be studied by examining this required interaction of prolyl-4-hydroxylase with procollagen. High-resolution...
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