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Mutation analysis of 218 Chinese patients with Wilson disease revealed no correlation between the canine copper toxicosis gene MURR1 and Wilson disease.

Journal of molecular medicine (Berlin, Germany) - 1 May 2006

Wu Zhi-Ying, Zhao Gui-Xian, Chen Wan-Jin, Wang Ning, Wan Bo, Lin Min-Ting, Murong Shen-Xing, Yu Long

Abstract excerpt

Wilson disease (WD) is the most common disorder resulting in hepatic copper overload. A similar form of copper-associated cirrhosis caused by mutations of the canine copper toxicosis MURR1 gene is also observed in Bedlington terriers. Recent studies indicate that MURR1 might influence human copper metabolism and the clinical presentations of WD. However, the correlation between the MURR1 gene and the Chinese...

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PMID: 16649058
DOI: 10.1007/s00109-005-0036-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Mutation analysis of 218 Chinese patients with Wilson disease revealed no correlation between the canine copper toxicosis gene MURR1 and Wilson disease.PMID 16649058Read ↗

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