Article
Indirect molecular diagnosis of copper toxicosis in Bedlington terriers is complicated by haplotype diversity.
The Journal of heredity - 1 Jan 2000
van de Sluis B, Peter A T, Wijmenga C
Abstract excerpt
Positional cloning recently identified the mutation causing copper toxicosis (CT) in Bedlington terriers. Isolation of the MURR1 gene will be of great value in developing a reliable diagnostic test for the breeding of a copper toxicosis-free stock. It will replace the current diagnostic test using the CT-linked marker, C04107, which is located in intron 1 of the MURR1 gene with a distance of approximately 8 kb...
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