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Article

Asynchronous expression of myeloid antigens in leukemic cells in a PML/RARalpha transgenic mouse model.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 May 2006

Santana B A A, Pintão M C, Abreu e Lima R S, Scheucher P S, Santos G A S, Garcia A B, Falcão R P, Rego E M

Abstract excerpt

Acute promyelocytic leukemia (APL) is characterized by the expansion of blasts that resemble morphologically promyelocytes and harbor a chromosomal translocation involving the retinoic acid receptor alpha (RARalpha) and the promyelocytic leukemia (PML) genes on chromosomes 17 and 15, respectively. The expression of the PML/RARalpha fusion gene is essential for APL genesis. In fact, transgenic mice (TM) expressing...

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Identifiers

PMID: 16648899
DOI: 10.1590/s0100-879x2006000500008

Genes

PML

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Asynchronous expression of myeloid antigens in leukemic cells in a PML/RARalpha transgenic mouse model.PMID 16648899Read ↗

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