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Article

Myeloid leukemia with promyelocytic features in transgenic mice expressing hCG-NuMA-RARalpha.

Oncogene - 22 Jan 2004

Sukhai Mahadeo A, Wu Xuemei, Xuan Yali, Zhang Tong, Reis Patricia P, Dubé Karina, Rego Eduardo M, Bhaumik Mantu, Bailey Denis J, Wells Richard A, Kamel-Reid Suzanne, Pandolfi Pier Paolo

Abstract excerpt

Acute promyelocytic leukemia (APL) is characterized by the accumulation of abnormal promyelocytes in the bone marrow (BM), and by the presence of a reciprocal chromosomal translocation involving retinoic acid receptor alpha (RARalpha). To date, five RARalpha partner genes have been identified in...

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Source

Identifiers

PMID: 14737102
DOI: 10.1038/sj.onc.1207073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14737102-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Myeloid leukemia with promyelocytic features in transgenic mice expressing hCG-NuMA-RARalpha.PMID 14737102Read ↗

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Asynchronous expression of myeloid antigens in leukemic cells in a PML/RARalpha transgenic mouse model.Semantic proximity Read ↗

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Transgenic expression of PML/RARalpha impairs myelopoiesis.Semantic proximity Read ↗

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