Article
Functional interaction of CP2 with GATA-1 in the regulation of erythroid promoters.
Molecular and cellular biology - 1 May 2006
Bosè Francesca, Fugazza Cristina, Casalgrandi Maura, Capelli Alessia, Cunningham John M, Zhao Quan, Jane Stephen M, Ottolenghi Sergio, Ronchi Antonella
Abstract excerpt
We observed that binding sites for the ubiquitously expressed transcription factor CP2 were present in regulatory regions of multiple erythroid genes. In these regions, the CP2 binding site was adjacent to a site for the erythroid factor GATA-1. Using three such regulatory regions (from genes encoding the transcription factors GATA-1, EKLF, and p45 NF-E2), we demonstrated the functional importance of the adjacent...
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