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Infection-associated type IV secretion systems ofBartonellaand their diverse roles in host cell interaction

19 May 2008

Abstract excerpt

Type IV secretion systems (T4SSs) are transporters of Gram-negative bacteria that mediate interbacterial DNA transfer, and translocation of virulence factors into eukaryotic host cells. The alpha-proteobacterial genus Bartonella comprises arthropod-borne pathogens that colonize endothelial cells and erythrocytes of their mammalian reservoir hosts, thereby causing long-lasting intraerythrocytic infections. The...

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PMID: 18489724
DOI: 10.1111/j.1462-5822.2008.01171.x

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