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Structural Characterization of the Type IV Secretion System in <i>Brucella melitensis</i> for Virtual Screening-Based Therapeutic Targeting

2026-02-18

Abstract excerpt

Brucellosis is a globally important zoonotic disease caused by Brucella melitensis , the most virulent and clinically significant species affecting both humans and livestock. Unlike many Gram-negative pathogens, B. melitensis , a facultative intracellular pathogen, lacks conventional virulence factors and instead relies on specialized systems such as the Type IV Secretion System (T4SS) for secretion of effector...

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Literature Corpus work
fcd3dc72-4f9b-5e6f-a2db-391723777715
DOI
10.64898/2026.02.18.706537
Open publication

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